Here's a game guide for slotting Empowered Iso-8 into Hero uniforms in the game Marvel: Avengers Alliance. Empowered Iso-8 grants new passive abilities to your heroes. Available on base uniforms at level 4 and 13 (2 slots), and other alternate uniforms at level 13 (1 slot only).
There are 3 types of Empowered ISO-8, Generic (Store: command points), Class Restricted (Store: gold), and Character Restricted (Heroic Battle: loot spin). Note that the below Empowered Iso-8s are just suggestions, and are not the only way to power-up heroes.
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- Empowered Isotope-8 Suggestions for Heroes -
IMPORTANT NOTES!
- Complete Heroic Battles with the required hero to get a chance to receive a Character Restricted ISO-8.
- [S2-C1-M1] means Season 2, Chapter 1, Mission 1.
- Note: Heroes with multiple suggestions: just select 1 or 2 Empowered Iso-8.
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- Season 1 Chapter 2 Empowered Iso-8 -
Fandral
- Character Restricted [S1-C2-M6] - Loquacious Empowered Iso-8
- Gift of the Buns: Master of puns; Witty Retort causes Migraine.
Hogun
- Character Restricted [S1-C2-M6] - Disciplined Empowered Iso-8
- Rigorous Training: Immune to Winded, Off-Balanced, Fumbling and Flanked.
Volstagg
- Character Restricted [S1-C2-M6] - Voracious Empowered Iso-8
- Food Fight: Gain one stack of Well Fed each round.
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- Season 2 Chapter 1 Empowered Iso-8 -
Gambit
- Character Restricted [S2-C1-M1] - Pilfered Empowered Iso-8
- Eight Card Stud: Gambit may gain 8 stacks of Kinetic Charge.
Rogue
- Character Restricted [S2-C1-M1] - Caressing Empowered Iso-8
- Roguelike: Starts Combat with Into the Fray.
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Wolverine
- Character Restricted [S2-C1-M2] - Soothing Empowered Iso-8
- Revivify: Extends Recharge to allow Wolverine to heal to full health once per battle.
Sabretooth
- Character Restricted [S2-C1-M2] - Frenzied Empowered Iso-8
- Riled Up: Gain Frenzy at the start of combat, but can't survive being KO'ed.
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Nightcrawler
- Character Restricted [S2-C1-M3] - Revered Empowered Iso-8
- Pious Prayer: Grants Mystic Shroud to team at start of combat.
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Spider-Woman
- Character Restricted [S2-C1-M4] - Tantalizing Empowered Iso-8
- True Love: Mind Control lasts an extra round; Targets with Mind Control will protect Spider-Woman more often.
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Hercules
- Character Restricted [S2-C1-M5] - Smiting Empowered Iso-8
- Marble Counter: Chance to counter area attacks with Column Down.
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Cable
- Character Restricted [S2-C1-M6] - Instant Empowered Iso-8
- Temporal Paradox: Chance to pre-counter attacks.
Deadpool
- Character Restricted [S2-C1-M6] - Spicy Empowered Iso-8
- Well Fed: That hit the spot (3 rounds).
- Lifepool: The first attack that would reduce Deadpool's health to 0 will return him to 50% health instead.
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- Season 2 Chapter 2 Empowered Iso-8 -
Dr. Strange
- Character Restricted [S2-C2-M1] - Enchanted Empowered Iso-8
- Baleful: Bolts of Balthakk exploit attrition.
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Daredevil
- Character Restricted [S2-C2-M2] - Tylphotic Empowered Iso-8
- Sensitive: Radar Sense grants Paragon Exploiter to Daredevil's attacks.
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Captain America
- Character Restricted [S2-C2-M3] - Fervent Empowered Iso-8
- Discus: Chance to counter ranged attacks with Shield Throw.
Ironman
- Character Restricted [S2-C2-M3] - Photoconductive Empowered Iso-8
- Capacitive Armor: Gains a Unibeam Focus when attacked with Energy or Electric attacks.
Thor
- Character Restricted [S2-C2-M3] - Dynamic Empowered Iso-8
- Thunder God: Inspire Bravery causes Static Charge on all enemies; Hammer Throw and Empowered Strike gain the Electricity Attack Type.
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Wolverine
- Character Restricted [S2-C2-M4] - Stalking Empowered Iso-8
- Hunting Instinct: When attacked with a Melee attack, applies Unique Scent to attacker; Enemies with Unique Scent can not be protected from or counter Wolverine's attacks; Wolverine has a higher chance to hit enemies with Unique Scent.
Deadpool
- Character Restricted [S2-C2-M4] - Savory Empowered Iso-8
- Still Better: Sharp Pointy Things applies 2 stacks of Bleeding.
- Come At Me, Bob: Chance to protect allies from single target attacks; Higher chance to protect with low health; Chance to counter attacks; higher chance to counter with high health.
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Spider-Man
- Character Restricted [S2-C2-M5] - Inventive Empowered Iso-8
- Smartest Man in the Room: Each round triggers a new Analysis.
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Quicksilver
- Character Restricted [S2-C2-M6] - Accelerating Empowered Iso-8
- Frictionless: Quickness is not consumed by counter attacks.
Scarlet Witch
- Character Restricted [S2-C2-M6] - Statistical Empowered Iso-8
- Controlled Chaos: Chaos Shield never misses and never fails.
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- Season 2 Chapter 3 Empowered Iso-8 -
Mr. Fantastic
- Character Restricted [S2-C3-M1] - Overclocked Empowered Iso-8
- Overclocked: Bifurcator hits all enemies.
Doctor Doom
- Character Restricted [S2-C3-M1] - Unbreakable Empowered Iso-8
- Will of Doom: Immune to Stun and Exhaustion.
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Ms. Marvel
- Character Restricted [S2-C3-M2] - Fixating Empowered Iso-8
- Fixating: Ms. Marvel's attacks gain Truestrike and Guaranteed Hit.
Moonstone
- Character Restricted [S2-C3-M2] - Analyzing Empowered Iso-8
- Psychoanalysis: Chance to counter attacks from enemies with Cower, Distracted, Disoriented, Intimidated, or Shell Shocked.
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Hawkeye
- Character Restricted [S2-C3-M3] - Attentive Empowered Iso-8
- Hawkeye's Initiative: Hawkeye will attempt to go first in combat.
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Phoenix
- Character Restricted [S2-C3-M4] - Consuming Empowered Iso-8
- Consuming Fire: Psi-Blast applies Soulfire.
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Black Panther
- Character Restricted [S2-C3-M5] - Flashing Empowered Iso-8
- Panther's Bite: Vibranium Daggers now grants Fang of the Panther; Panther Stance now grants Roar of the Panther.
Black Widow
- Character Restricted [S2-C3-M5] - Androit Empowered Iso-8
- Lithe: Martial Arts Combo gains Disadvantage.
Wasp
- Character Restricted [S2-C3-M5] - Irritating Empowered Iso-8
- Swarming: 100% chance to Counter any enemy with Staggered, Distraction, Odd-balance, Cornered or Dizzy that attacks Wasp or an ally.
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Black Cat
- Character Restricted [S2-C3-M6] - Lucky Empowered Iso-8
- Lands on Her Feet: Stroke of Luck has a chance of granting Black Cat and extra turn.
Spider-Man
- Character Restricted [S2-C3-M6] - Tangled Empowered Iso-8
- Entangling: Webbed has a chance to cause Staggered, Distraction, Off-balance, or Dizzy.
- Loaded Sling: Web Slingshot exploits Opportunist.
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- Season 2 Chapter 4 Empowered Iso-8 -
Emma Frost
- Character Restricted [S1-C4-M1] - Eternal Empowered Iso-8
- Diamonds Are Forever: Diamond Body no longer triggers Organic Recovery.
Magneto
- Character Restricted [S1-C4-M1] - Fluxing Empowered Iso-8
- Superconductor: Replace Magnetized with Polarized, which cannot be removed or prevented.
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Hulk
- Character Restricted [S2-C4-M2] - Thick Empowered Iso-8
- Bulk Up: Reduces damage taken for each Hulk Up.
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Sif
- Character Restricted [S2-C4-M3] - Berserking Empowered Iso-8
- Berserker: Chance to join in on an ally's attack; Chance to retaliate when an ally is hit by single-target attacks.
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Colossus
- Character Restricted [S2-C4-M4] - Decimating Empowered Iso-8
- Atomic Buster: Chance to counter single target and area attacks with Decimate.
Cyclops
- Character Restricted [S2-C4-M4] - Commanding Empowered Iso-8
- Inspiring Leadership: Provides Inspiring leadership to all allies, increasing all stats.
Storm
- Character Restricted [S2-C4-M4] - Windy Empowered Iso-8
- Wind Shear: Grants Protective Shroud to all allies at the start of combat.
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Captain Britain
- Character Restricted [S2-C4-M5] - Knightly Empowered Iso-8
- Pendragon: Increases the chance for Roar of Valor to reduce damage.
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Mockingbird
- Character Restricted [S2-C4-M6] - Predictive Empowered Iso-8
- Prediction: Mock Combat triggers before an enemy's attack.
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- Season 2 Chapter 5 Empowered Iso-8 -
She-Hulk
- Character Restricted [S2-C5-M1] - Furiouse Empowered Iso-8
- Getting Angry: Gains Hulk Up each round; Gains Hulk Up each when attacked.
Thundra
- Character Restricted [S2-C5-M1] - Resolute Empowered Iso-8
- Indomitable Spirit: Suppresses most effects that prevent or remove buffs.
Tigra
- Character Restricted [S2-C5-M1] - Predatory Empowered Iso-8
- Huntress: Chance to perform Swipe as a follow-up on single-target attacks.
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Kitty Pryde
- Character Restricted [S2-C5-M2] - Dragonian Empowered Iso-8
- Lockdown: Counters all attacks with Lockheed while not Phased.
X-23
- Character Restricted [S2-C5-M2] - Aromatic Empowered Iso-8
- Killer Instinct: Preemptively applies Trigger Scent when attacking if X-23 doesn't have Berserker Rage.
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Human Torch
- Character Restricted [S2-C5-M3] - Pyroclastic Empowered Iso-8
- Firestarter: Attacks against Burning targets apply Pyrophoric; Attacks against Pyrophoric targets apply Melt Armor.
Invisible Woman
- Character Restricted [S2-C5-M3] - Circulating Empowered Iso-8
- Air Pressure: Party members with shields remove and prevent debuffs while shields are active.
Thing
- Character Restricted [S2-C5-M3] - Masonic Empowered Iso-8
- Yancy Street Rules: Begin the flight with Stonewall; Stone Wall reduces damage received.
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Bishop
- Character Restricted [S2-C5-M4] - Dynamo Empowered Iso-8
- Focused Efforts: All Normal Actions generate 1 additional Potential Energy.
Havok
- Character Restricted [S2-C5-M4] - Grounding Empowered Iso-8
- Strategic Thinking: Protects allies from Energy attacks.
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Fantomex
- Character Restricted [S2-C5-M5] - Duplicitous Empowered Iso-8
- Gentleman Cambrioleur: Performs a follow-up attack when enemies attack each other.
- Character Restricted [S2-C5-M5] - Synchronized Empowered Iso-8
- Mental Preparation: Allies begin the fight with Mental Coordination.
Spiral
- Character Restricted [S2-C5-M5] - Rhythmic Empowered Iso-8
- Shall We Dance: All dance actions are available as a multi-action.
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Hulk
- Character Restricted [S2-C5-M6] - Ironclad Empowered Iso-8
- Bastion: Chance to take reduced damage and resist crits from attacks.
- Character Restricted [S2-C5-M6] - Smoldering Empowered Iso-8
- Boomshakalaka!: Begins the fight with 40% Heat.
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- Season 2 Chapter 6 Empowered Iso-8 -
Captain America
- Character Restricted [S2-C6-M1] - Leading Empowered Iso-8
- The First Avenger: Captain America will attempt to go first in combat.
Falcon
- Character Restricted [S2-C6-M1] - Swooping Empowered Iso-8
- Nimble: 50% chance to avoid melee and ranged attacks for 2 rounds.
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Ghost Rider
- Character Restricted [S2-C6-M2] - Tenacious Empowered Iso-8
- From Hell: The first attack that would reduce Ghost Rider's health to 0 will return him to 50% health instead.
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Ares
- Character Restricted [S2-C6-M3] - Desperate Empowered Iso-8
- Tides of War: Are's attack gain Desperation Attack.
War Machine
- Character Restricted [S2-C6-M3] - Tactical Empowered Iso-8
- Strategic Advantage: Strategic Analysis also applies Disadvantage.
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Daimon Hellstrom
- Character Restricted [S2-C6-M4] - Hellacious Empowered Iso-8
- From Hell: The first attack that would reduce Ghost Rider's health to 0 will return him to 50% health instead.
Satana
- Character Restricted [S2-C6-M4] - Enticing Empowered Iso-8
- Sweet Nothings: Chance to preemptively apply Distracted when an enemy attacks.
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Punisher
- Character Restricted [S2-C6-M5] - Prepared Empowered Iso-8
- Real Combat: When attacked, preemptively chances class to the attacker's counter-class; Not triggered by counter-attacks.
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Iron Fist
- Character Restricted [S2-C6-M6] - Heartfelt Empowered Iso-8
- Killer Instinct: Combo Breaker has a 100% chance.
Luke Cage
- Character Restricted [S2-C6-M6] - Enticing Empowered Iso-8
- Street Cleaner: Remove 1 negative effect when Knuckle-Up is gained.
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- Season 2 Chapter 7 Empowered Iso-8 -
Magik
- Character Restricted [S2-C7-M1] - Bloodshot Empowered Iso-8
- Evil Eye: Summoned Eyebites now apply Breakdown.
Omega Sentinel
- Character Restricted [S2-C7-M1] - Indexing Empowered Iso-8
- Iso Inside: Chance to gain the positive aspects of the target's class when attacked.
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Black Cat
- Character Restricted [S2-C7-M2] - Startling Empowered Iso-8
- Deja vu: Grants a follow-up attacks to single-target attacks if the target is Bleeding.
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Beast
- Character Restricted [S2-C7-M3] - Pacifying Empowered Iso-8
- A Separate Peace: Regain health on any turn Beast does not attack.
Hank Pym
- Character Restricted [S2-C7-M3] - Diminutive Empowered Iso-8
- Size Matters: 20% chance to shrink to avoid incoming attacks.
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Heimdall
- Character Restricted [S2-C7-M4] - Halting Empowered Iso-8
- Impasse: Chance to preemptively negate counter attacks.
Valkyrie
- Character Restricted [S2-C7-M4] - Unwavering Empowered Iso-8
- Champion of the Slain: Increases Accuracy, Attack, Defense, and Evasion when an ally is KO'ed.
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Doctor Voodoo
- Character Restricted [S2-C7-M5] - Spiritual Empowered Iso-8
- Spirit Field: Grants Spirit Field to all allies at the start of combat; Incoming area damage reduced by 30%.
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Black Knight
- Character Restricted [S2-C7-M6] - Shielding Empowered Iso-8
- Defensive Stance: Has a chance to block attacks, taking reduced damage.
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- Season 2 Chapter 8 Empowered Iso-8 -
Bishop
- Character Restricted [S2-C8-M1] - Energized Empowered Iso-8
- Ambient Energy: Gains potential energy when allies use energy attacks.
Cable
- Character Restricted [S2-C8-M1] - Thoughtful Empowered Iso-8
- Thoughtful: Psychic attacks are guaranteed to hit.
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Vision
- Character Restricted [S2-C8-M2] - Immaterial Empowered Iso-8
- Immaterial: Increased chance to counter attack and become phased.
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Molly Hayes
- Character Restricted [S2-C8-M3] - Sweet Empowered Iso-8
- Sweet: Chance to eat left over Halloween candy before her turn.
Nico Minoru
- Character Restricted [S2-C8-M3] - Gasping Empowered Iso-8
- Second to Last Gasp: Restores health to remaining allies when defeated in combat for the first time.
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Shatterstar
- Character Restricted [S2-C8-M4] - Corybantic Empowered Iso-8
- Warbringer: Grants Warbound to all allies; Warbound allies gain War Frenzy when attacked, increasing attack and accuracy.
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Union Jack
- Character Restricted [S2-C8-M5] - Bounding Empowered Iso-8
- Bounding: Gain a damage boost after a successful counter of a follow-up attack.
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Kang
- Character Restricted [S2-C8-M6] - Cybernetic Empowered Iso-8
- Cybernetic: Immune to bleeding, burning, chilled, and obsolete tech; Very high Crit resistance.
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- Season 2 Chapter 9 Empowered Iso-8 -
Angela
- Character Restricted [S2-C9-M1] - Ardent Empowered Iso-8
- Blood lust: Recover 100% health when Angela knocks out an enemy.
Beta Ray Bill
- Character Restricted [S2-C9-M1] - Rumbling Empowered Iso-8
- The Thunder Rolls: After attacking, chance for a follow-up lightning strike that causes static charge.
Loki
- Character Restricted [S2-C9-M1] - Tricky Empowered Iso-8
- Blue Deck: When an enemy attempts a magic action, Loki has a chance to prevent and counter that action.
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Elektra
- Character Restricted [S2-C9-M2] - Coercive Empowered Iso-8
- Ninja Fury: Gains scrappy sentiment when attacked.
Ghost Rider
- Character Restricted [S2-C9-M2] - Ferocious Empowered Iso-8
- Fury Road: Gains bruised benefit when attacked.
Red Hulk
- Character Restricted [S2-C9-M2] - Acclimatized Empowered Iso-8
- Cool Under Pressure: Meltdown only damages enemies; Meltdown no longer stuns Red Hulk.
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Agent Venom
- Character Restricted [S2-C9-M3] - Assertive Empowered Iso-8
- Squad Leader: Combat awareness given to all allies at the beginning of each turn.
Anti-Venom
- Character Restricted [S2-C9-M3] - Shifty Empowered Iso-8
- Symbiotic Flow: Chance to avoid incoming attacks.
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Fandral
- Character Restricted [S2-C9-M4] - Convivial Empowered Iso-8
- All For One: Chance to join in ally's single-target attack; Chance to retaliate when an ally is hit by single-target attacks.
Hogun
- Character Restricted [S2-C9-M4] - Militant Empowered Iso-8
- Warlord: Grants Warbound to all allies; Warbound allies gain War Frenzy when attacked, increasing attack and accuracy.
Volstagg
- Character Restricted [S2-C9-M4] - Nourished Empowered Iso-8
- Big Breakfast: Start combat with 13x well fed and man in the middle.
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Daredevil
- Character Restricted [S2-C9-M5] - Cogitative Empowered Iso-8
- Rapid Rebuttal: Take an extra turn when attacked with a melee attack.
Moon Knight
- Character Restricted [S2-C9-M5] - Reprising Empowered Iso-8
- Retributioner: Gain 1 Retribution whenever anyone attacks.
Sandman
- Character Restricted [S2-C9-M5] - Barricaded Empowered Iso-8
- Sandstone: Protect allies from single target attacks; Gains Grit when attacked.
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Wonder Man
- Character Restricted [S2-C9-M6] - Averting Empowered Iso-8
- Ionic Wall: Protect allies from area attacks.
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- Season 2 Chapter 10 Empowered Iso-8 -
Constrictor
- Character Restricted [S2-C10-M1] - Serpentine Empowered Iso-8
- Coiled and Ready: Chance to counter any attacking enemies with Lightninglash.
Hercules
- Character Restricted [S2-C10-M1] - Lasting Empowered Iso-8
- Vigor: Applies Rising Up at the beginning of each turn while stamina is full; Likes it Rough now has 100% chance to restore stamina when attacked.
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Chase Stein
- Character Restricted [S2-C10-M2] - Bonded Empowered Iso-8
- Inseparable: Starts combat with 5 stacks of Empathic Bond.
Victor Mancha
- Character Restricted [S2-C10-M2] - Calculating Empowered Iso-8
- One Step Ahead: Starts combat with Crackling Sheild and static cling.
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Captain Britain
- Character Restricted [S2-C10-M3] - Otherworldly Empowered Iso-8
- Merlin's Wisdom: Protects allies from single target attacks; Chance to apply Curse of the Otherworld in enemies that attack Captain Britain.
Kitty Pryde
- Character Restricted [S2-C10-M3] - Scalded Empowered Iso-8
- Dragonfire: Chance to follow-up attacks with Call Lockheed.
Ultimate Spider-Man
- Character Restricted [S2-C10-M3] - Astute Empowered Iso-8
- Quick Thinking: Gain an extra turn after attacking a stunned target.
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Blade
- Character Restricted [S2-C10-M4] - Strident Empowered Iso-8
- All Nighter: Start combat with Quickening, Burst of Speed and Vampiric Thirst.
Morbius
- Character Restricted [S2-C10-M4] - Proved Empowered Iso-8
- Improved Formula: Chance for a Positive Chemical Reaction at the beginning of each turn.
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Magneto
- Character Restricted [S2-C10-M5] - Overshadowed Empowered Iso-8
- Great Leader: Chance of applying Moral Boost and Combat Awareness on allies that are attacked.
Mr. Fantastic
- Character Restricted [S2-C10-M5] - Canny Empowered Iso-8
- Shared Research: Applies an Analysis Buff on all allies at the beginning of each turn; Each application triggers a new Analysis: Research Proposal, Research Study, Research Paper.
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Black Bolt
- Character Restricted [S2-C10-M6] - Ripped Empowered Iso-8
- Silent But Deadly: Applies Buildup after performing a range attack; Applies Rising Up after performing a melee attack.
Medusa
- Character Restricted [S2-C10-M6] - Crinal Empowered Iso-8
- In the Cross Hairs: Counters Tied Up enemies with Splitting Hairs.
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- Store Only Character Restricted Empowered Iso-8 -
Cyclops
- Character Restricted [Store-Gold Only] - Optical Empowered Iso-8
- Oversight: Optic Blast and Mega Optic Blast Ignore Defense.
Daimon Hellstrom
- Character Restricted [Store-Gold Only] - Imprudent Empowered Iso-8
- Steadfast Soul: Immune to opportunist debuffs.
Daredevil
- Character Restricted [Store-Gold Only] - Assailing Empowered Iso-8
- Assailant: Chance to perform a follow-up attack against Weakened, Exposed, Dizzy or Slowed targets.
Ironfist
- Character Restricted [Store-Gold Only] - Masterful Empowered Iso-8
- Living Weapon: K'un L'un Combo and Five fingers of Death apply Pressure Points.
Luke Cage
- Character Restricted [Store-Gold Only] - Tag Team Empowered Iso-8
- Tag Team: 15% chance to gain an extra turn after an ally's melee attack.
Mockingbird
- Character Restricted [Store-Gold Only] - Chameleonic Empowered Iso-8
- Blending In: 100% chance to gain extra turn when changing classes.
- Character Restricted [Store-Gold Only] - Flooded Empowered Iso-8
- Briny Deep: Start combat with rising tide; All attacks gain Exploit Waterlogged.
Ms. Marvel
- Character Restricted [Store-Gold Only] - Realized Empowered Iso-8
- Full Potential: Hidden Potential also triggers on Elemental, Kinetic and Psychic attacks.
Scarlet Witch
- Character Restricted [Store-Gold Only] - Fortuitous Empowered Iso-8
- Get Lucky: Chance to manipulate probability, dodging attacks, countering attacks, following-up attacks, ignoring enemy defense; Chance to make Chaos Shield a Quick Action.
She-Hulk
- Character Restricted [Store-Gold Only] - Objecting Empowered Iso-8
- Cross-Examination: Chance to prevent enemy attacks.
Spider Woman
- Character Restricted [Store-Gold Only] - Rising Empowered Iso-8
- Re-Vengeance: Vengeance and Worthy Vengeance are guaranteed to counter melee and range attacks.
- Character Restricted [Store-Gold Only] - Runic Empowered Iso-8
- Runekeeper: Runes are no longer consumed when they explode.
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Related Marvel: Avengers Alliance Tips & Guides:
Marvel: Avengers Alliance: Character Restricted Augmented Iso-8 Drops
Marvel: Avengers Alliance: Suggested ISO-8 Stats for Heroes
Marvel: Avengers Alliance: Suggested Reactive (Tier 5) ISO-8 for Heroes
Marvel: Avengers Alliance: Suggested ISO-8 Stats for Agents
Marvel: Avengers Alliance: How to Unlock ISO-8 Technology
Marvel: Avengers Alliance: Recommended Heroes to Get
Marvel: Avengers Alliance: Best, Top and Most Used Heroes Per Class
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