All mission objectives in Astro Boy Dash game are not cumulative, you need to complete all of them within a single run. Meet the requirements or conditions to successfully mark them as complete.
Some missions will be completed once you reach a milestone, to do this, upgrade your Power-Ups and Character Upgrades while progressing through the game to help you survive longer, giving you a better chance to complete hard missions.
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Missions That Requires You to Run a Number of Meters
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Astro Boy Dash: Quick Walkthrough, Upgrades, and Strategy Guide